Items tagged with Drug-resistant TB
A Tuberculosis Guide for Specialist Physicians (document)
This document discusses the need for cooperation between tuberculosis control programmes and specialist physicians and the important role of specialist physicians have in an NTP. Each chapter covers critical topics in TB including: epidemiology, pathogenesis, diagnosis, treatment, re-treatment, drug resistance, control, and special populations (HIV, elderly).
MDR, XDR, TDR tuberculosis: ominous progression (document)
Zarir Udwadia writes in *Thorax* about an extremely drug resistant strain of TB in India. He writes: > Thus, decades of mismanagement of MDR-TB at government and private care levels have resulted in amplification of the level of resistance till we have finally ended up with a virtually untreatable strain.
Management of patients with multidrug-resistant/extensively drug-resistant tuberculosis in Europe: a TBnet consensus statement (document)
The document summarises the current knowledge on the prevention, diagnosis and treatment of adults and children with MDR/XDR-TB and their contacts, and provides expert consensus recommendations on questions where scientific evidence is still lacking.
Time of great change in TB drug development (post with simple image)
We are living in a time of great change and excitement in TB drug development. The last year has witnessed a number of epochal changes, including the approval and rollout of the most rapid test for TB ever discovered, the GeneXpert; the combination TB drug studies in the relapse mouse model of Eric Nuermberger and Jacques Grosset at Johns Hopkins with support from the TB Alliance; the progression of TMC207 into late phase II and of OPC67683 into phase III; and the first new regimen EBA study, NC-001 also from the Alliance.
Totally Drug Resistant TB strain turns up in patients in India (post with simple image)
Doctors at the Hinduja National Hospital and Research Centre in Mumbai, India, are reporting on a strain of tuberculosis (TB) emerging among patients that is resistant to all first- and second-line drugs used to treat the bacterial infection. At least twelve patients have been identified so far. The doctors do not present evidence that the resistant strain is passing from human to human, and mostly focus on how TDR can develop in TB infected individuals due to poor treatment management.
South Africa: XDR-TB spreading as uncured patients go home (post with simple image)
Extensively drug-resistant tuberculosis (XDR-TB) appears to be spreading in South Africa, fueled by patients who are discharged despite failing therapy, researchers reported.
Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults (post with simple image)
A second systematic review of a diagnostic test for TB endorsed by WHO, has confirmed the accuracy of the test. Xpert® MTB/RIF is more accurate than smear microscopy for diagnosing TB and also accurate for detecting rifampicin resistance.
Russia's drug-resistant TB spreading more easily (post with simple image)
Newly discovered mutations help tuberculosis to stay infectious while evolving resistance to multiple drugs.
An ounce of gold for a pound of cure (post with simple image)
It's around our necks and on our fingers, traded by our banks and used to make our electronics. Yet for a huge swath of people around the globe, gold's impact is felt in the lungs.
Point-of-care diagnostics for tuberculosis elimination? (post with simple image)
The projected epidemiological effect of Xpert MTB/RIF might be overestimated, so this fascinating and promising new tool is unlikely to be the magic bullet that paves the way towards tuberculosis elimination.
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